National Cancer Institute, Baltimore Cancer Research Center, Baltimore, MD
Certification:
Internal Medicine, Medical Oncology
Contact
Information:
Mailing Address:
Room 9-031 Bressler Research Building,
655 West Baltimore Street,
Baltimore, MD 21201
Email:
dross@som.umaryland.edu
Phone:
410-328-3685; 410-325-8095
Fax:
410-328-6559
Research Interests:
Mechanisms of cancer cellular resistance to antineoplastic agents; Transporter-based multidrug resistance; Early phase clinical trials.
Palliative care, and education of medical students, residents and medical oncology fellows on palliative care topics
Publications:
Krishnamurthy P, Ross DD, Nakanishi T, Bailey-Dell K, Zhou S, Mercer KE, Sarkadi B, Sorrentino BP, Schuetz JD. The stem cell marker Bcrp/ABCG2 enhances hypoxic cell survival through interactions with heme. J Biol Chem. 2004 Jun 4;279(23):24218-25. Epub 2004 Mar 24. PMID: 15044468 [PubMed - indexed for MEDLINE]
Ee PL, Kamalakaran S, Tonetti D, He X, Ross DD, Beck WT. Identification of a novel estrogen response element in the breast cancer
resistance protein (ABCG2) gene. Cancer Res. 2004 Feb 15;64(4):1247-51. PMID: 14973083 [PubMed - indexed for MEDLINE]
Nakanishi T, Doyle LA, Hassel B, Wei Y, Bauer KS, Wu S, Pumplin DW, Fang HB, Ross DD. Functional characterization of human breast cancer resistance protein (BCRP,ABCG2) expressed in the oocytes of Xenopus laevis. Mol Pharmacol. 2003 Dec;64(6):1452-62. PMID: 14645676 [PubMed - indexed for MEDLINE]
Nakanishi T, Karp JE, Tan M, Doyle LA, Peters T, Yang W, Wei D, Ross DD. Quantitative analysis of breast cancer resistance protein and cellular
resistance to flavopiridol in acute leukemia patients. Clin Cancer Res. 2003 Aug 15;9(9):3320-8. PMID: 12960118 [PubMed - indexed for MEDLINE]
Ross DD, Fraser HC, Kutner JS. Institutionalization of a palliative and end-of-life care educational program in a medical school curriculum. J Palliat Med. 2001 Winter;4(4):512-8. PMID: 11798486 [PubMed - indexed for MEDLINE]
Bailey-Dell KJ, Hassel B, Doyle LA, Ross DD. Promoter characterization and genomic organization of the human breast cancer
resistance protein (ATP-binding cassette transporter G2) gene. Biochim Biophys Acta. 2001 Sep 21;1520(3):234-41. PMID: 11566359 [PubMed - indexed for MEDLINE]
Ross DD, Karp JE, Chen TT, Doyle LA. Expression of breast cancer resistance protein in blast cells from patients with acute leukemia. Blood. 2000 Jul 1;96(1):365-8. PMID: 10891476 [PubMed - indexed for MEDLINE]
Rabindran SK, Ross DD, Doyle LA, Yang W, Greenberger LM. Fumitremorgin C reverses multidrug resistance in cells transfected with the
breast cancer resistance protein. Cancer Res. 2000 Jan 1;60(1):47-50. PMID: 10646850 [PubMed - indexed for MEDLINE]
Ross DD, Keay T, Timmel D, Alexander C, Dignon C, O'Mara A, O'Brien W 3rd. Required training in hospice and palliative care at the University of Maryland School of Medicine. J Cancer Educ. 1999 Fall;14(3):132-6. PMID: 10512327 [PubMed - indexed for MEDLINE]
Doyle LA, Yang W, Abruzzo LV, Krogmann T, Gao Y, Rishi AK, Ross DD. A multidrug resistance transporter from human MCF-7 breast cancer cells.
Proc Natl Acad Sci U S A. 1998 Dec 22;95(26):15665-70. Erratum in: Proc Natl
Acad Sci U S A 1999 Mar 2;96(5):2569. PMID: 9861027 [PubMed - indexed for MEDLINE]
Ross DD, O'Mara A, Pickens N, Keay T, Timmel D, Alexander C, Hawtin C, O'Brien W 3rd, Schnaper N. Hospice and palliative care education in medical school: a module on the role of the physician in end-of-life care. J Cancer Educ. 1997 Fall;12(3):152-6. PMID: 9376252 [PubMed - indexed for MEDLINE]