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Researcher Information

Agnes Marie Azimzadeh (Isabey) , Ph.D.
Assistant Professor

Department:
Surgery

UMGCC Research Program:
Tumor Immunology and Immunotherapy
Experimental Therapeutics Program

Education/Training:
College Degree: University Louis Pasteur, Strasbourg, France
Post Doctoral Degree: University Louis Pasteur, Strasbourg, France
Fellowship: Institute of Transplantation, Strasbourg, France
Publications:
Ndejembi MP, Patke DS, Bingaman AW, Chandock MR, Azimzadeh A, Nadler SG, Farber DL. (2006) Memory CD4 T cell recall and survival are susceptible to CD28/B7-mediated costimulation blockade. J. Immunol., 177:7698-706.

Wu G, Pfeiffer S, Schroder C, Zhang T, Nguyen BN, Kelishadi S, Atkinson JB, Schuurman HJ, White DJ, Azimzadeh AM, Pierson RNIII. (2007) Coagulation cascade activation triggers early failure of pig hearts expressing human complement regulatory genes. Xenotransplantation, 14:34-47.

Nguyen BN, Azimzadeh AM, Zhang T, Wu G, Shuurman HJ, Sachs DH, Ayares D, Allan JS, Pierson RN. (2007) Life-supporting function of genetically modified swine lungs in baboons. J. Thorac. Cardiovasc. Surg., 133:1354-63.

Schröder C , Pierson RNIII, Nguyen BN, Kawka DW, Peterson LB, Wu G, Zhang T, Springer MS, Siciliano SJ, Iliff S, Ayala JM, Lu M, Mudgett JS, Lyons K, Mills SG, Miller GG, Singer II, Azimzadeh AM, DeMartino JA. (2007) CCR5 blockade modulates inflammation and alloimmunity in primates. J. Immunol. 179:2289-99.

Barrows BR, Azimzadeh AM, Zhou H, Vives-Rodriguez G, McCulle SL, Stark WN, Ambulos N, Yin J, Richard N. Pierson, RN III, Johnson FL, Balke CW, Gottlieb SS, and Bond M. (2007) Robust gene expression analysis using amplified RNA from biopsy-sized human heart tissue. J Mol Cell Cardiol.,42: 260-264.

Chess DJ, Lei B, Hoit BD, Azimzadeh AM, Stanley WC. (2007) Deleterious effects of sugar and protective effects of starch on cardiac remodeling, contractile dysfunction, and mortality in response to pressure overload. Am J Physiol Heart Circ Physiol., 293:H1853-60.

Duda MK, O'Shea KM, Lei B, Barrows BR, Azimzadeh AM, McElfresh TE, Hoit BD,Kop WJ, Stanley WC. (2007) Dietary supplementation with omega-3 PUFA increases adiponectin and attenuates ventricular remodeling and dysfunction with pressure overload. Cardiovasc Res., 76:303-10.

Chess DJ, Lei B, Hoit BD, Azimzadeh AM, Stanley WC. (2008) Effects of a high saturated fat diet on cardiac hypertrophy and dysfunction in response to pressure overload. J Card Fail., 14:82-8.

Duda MK, O'Shea KM, Lei B, Barrows BR, Azimzadeh AM, McElfresh TE, Hoit BD,Kop WJ, Stanley WC. (2008) Low-carbohydrate/high-fat diet attenuates pressure overload-induced ventricular remodeling and dysfunction. J Card Fail.,14:327-35.

Sharma N, Okere IC, Barrows BR, Lei B, Duda MK, Yuan CL, Previs SF, Sharov VG, Azimzadeh AM, Ernsberger P, Hoit BD, Sabbah H, Stanley WC. (2008) High-sugar diets increase cardiac dysfunction and mortality in hypertension compared to low-carbohydrate or high-starch diets. J Hypertens., 26:1402-10.

Silverman RP, Banks ND, Detolla LJ, Shipley ST, Panda A, Sanchez RA, Azimzadeh AM, Pierson RN 3rd, Wang D, Rodriguez ED, Holton LH 3rd, Bartlett ST. (2008) A heterotopic primate model for facial composite tissue transplantation. Ann Plast Surg., 60:209-16.

Tang AL, Teijaro JR, Njau MN, Chandran SS, Azimzadeh A, Nadler SG, Rothstein DM, Farber DL. (2008) CTLA4 expression is an indicator and regulator of steady-state CD4+ FoxP3+ T cell homeostasis.J Immunol., 181:1806-13.