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Researcher Information

Richard Y. Zhao, Ph.D.
Associate Professor

Department:
Pathology

UMGCC Research Program:
Molecular and Structural Biology Program
Viral Oncology

Education/Training:
Medical Degree: Oregon State University

Contact Information:

Mailing Address: UM Greenebaum Cancer Center
Medical School Teaching Facility
Room 6-00E
Baltimore, MD 21201
Email: rzhao@som.umaryland.edu
Phone: 410-706-6300
Fax: 410-706-6302

Research Interests:
The role of HIV-1 viral protein R (Vpr) in cell cycle G2/M controls and anti-cancer therapy

Publications:
Finan, J. and Zhao, R.Y. 2007. Molecular diagnostics to personalized medicine (invited review). Pharmacogenomics. 8(1):85-99.

Zelivianski, S, D. Liang, M. Chen, B. L. Mirkin, R.Y. Zhao. 2006. Suppressive Effect of Elongation Factor 2 on Apoptosis Induced by HIV-1 Viral Protein R. Apoptosis. 11(3):377-88.

Zhang, Y., Qin, K., Wang, J., Hung, T.*, and R. Y. Zhao*. 2006. Dividing Roles of Prion Protein in Staurosporine-mediated Apoptosis. Biochemical and Biophysical Research Communication, 349(2):759-768. (*, co-corresponding author)

Qin, K. L. Zhao, Y. Tang, S. Bhatta, J. M. Simard, R.Y. Zhao. 2006. Doppel-induced apoptosis and counteraction by cellular prion protein in neuroblastoma and astrocytes. Neuroscience. 141(3):1375-1388.

Qin, K., M. ODonnell, and R.Y. Zhao. 2006. Doppel: More Rival than Double to Prion. Neuroscience. 141(1):1-8.

Fenyvesvolgyi, C. R.T. Elder, Z. Benko, D. Liang, and R.Y. Zhao. 2005. Fission yeast homologue of Tip41-like proteins regulates type 2A phosphatases and responses to nitrogen sources. Biochimica et Biophysica Acta. 1746(2):155-62.

Daniel, R. E. Marusich, E. Argyris, R.Y. Zhao, A.M. Skalka and R.J. Pomerantz. 2005. Caffeine inhibits human immunodeficiency virus type 1 transduction of nondividing cells. Journal of Virology. 79(4):2058-65.

Zhao, R.Y., and R.T. Elder. 2005. Viral Infections and cell cycle G2/M regulation (invited review). Cell Research. 15(3):143-9.

Zhao, R.Y. 2005. From single cell gene-based diagnostics to diagnostic genomics: current applications and future perspectives. Clinical Laboratory Sciences. 18(4):254-262.

Li, L., Li, H., C.D. Pauza, M. Bukrinsky and R.Y. Zhao. 2005. HIV-host interaction: role of accessory proteins. In: HIV/AIDS in China R.Y. Zhao (ed.). Cell Research. 15(11-12):923-934.

Benko, Z., D. Liang, E. Agbottah, J. Hou, K. Chiu, M. Yu, S. Innis, P. Reed, W. Kabat, R.T. Elder, P. Di Marzio, Ratner, P.G. Young, M. Bukrinsky and R. Y. Zhao. 2004. Anti-Vpr activity of a yeast chaperone protein. Journal of Virology. 78(20):11016-11029.

Iordanskiy, S., R.Y. Zhao, L. Dubrovsky, T. Iordanskaya, M. Chen, D. Liang, and M. Bukrinsky. 2004. Heat-shock protein 70 protects cells from HIV-1 infection by targeting viral protein R. Journal of Virology. 78(20):9697-9704.

Iordanskiy, S.*, R.Y. Zhao*, P. DiMarzio, I. Agostini, L. Dubrovsky, and M. Bukrinsky. 2004. Heat-shock protein 70 exerts opposite effects on Vpr-dependent and Vpr-independent HIV-1 replication in macrophages. Blood 104(6):1867-1872. (* co-first author).

Bukrinsky, M. and R.Y. Zhao. 2004. Heat-shock proteins reverse the G2 arrest caused by HIV-1 viral protein R. DNA and Cell Biology. 23(4):223-5.